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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">usfd</journal-id><journal-title-group><journal-title xml:lang="ru">Ультразвуковая и функциональная диагностика</journal-title><trans-title-group xml:lang="en"><trans-title>Ultrasound &amp; Functional Diagnostics</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-0771</issn><issn pub-type="epub">2408-9494</issn><publisher><publisher-name>Vidar Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24835/1607-0771-339</article-id><article-id custom-type="elpub" pub-id-type="custom">usfd-339</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Ультразвуковая диагностика в акушерстве и гинекологии</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Obstetrics and Gynecology Ultrasound</subject></subj-group></article-categories><title-group><article-title>Ультразвуковые показатели кровотока в глазных и почечных артериях во время раннего и второго пренатального скринингов у пациенток с высоким и низким риском развития преэклампсии</article-title><trans-title-group xml:lang="en"><trans-title>Ultrasound parameters of ophthalmic and renal maternal blood flow at first and second prenatal screening in patients with high and low risk of preeclampsia</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9569-3334</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Буланова</surname><given-names>М. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Bulanova</surname><given-names>M. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Буланова Мария Михайловна – аспирант кафедры акушерства и гинекологии факультета фундаментальной медицины Медицинского научно-образовательного института ФГБОУ ВО “Московский государственный университет имени М.В. Ломоносова”; врач ультразвуковой диагностики отделения антенатальной охраны плода Перинатального центра ГБУЗ “Городская клиническая больница №67 имени Л.А. Ворохобова ДЗ города Москвы”, Москваhttps://orcid.org/0000-0002-9569-3334</p></bio><bio xml:lang="en"><p>Maria M. Bulanova – MD, PhD student of the Obstetrics and Gynecology department, Faculty of medicine, Medical Research and Educational Institution, Lomonosov Moscow State University; ultrasound diagnostics specialist of the Antenatal fetal care department, Perinatal Centre, L.A. Vorohobov City Clinical Hospital No. 67, Moscowhttps://orcid.org/0000-0002-9569-3334</p></bio><email xlink:type="simple">mariabulanova98@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0008-6757-7660</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шамугия</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shamugiya</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шамугия Валериан Валерианович – канд. мед. наук, заведующий отделением антенатальной охраны плода Перинатального центра ГБУЗ “Городская клиническая больница №67 имени Л.А. Ворохобова ДЗ города Москвы”, Москваhttps://orcid.org/0009-0008-6757-7660</p></bio><bio xml:lang="en"><p>Valerian V. Shamugiya – MD, Cand. of Sci. (Med.), Head of the Antenatal fetalcare department, Perinatal Centre, L.A. Vorohobov City Clinical Hospital No. 67, Moscowhttps://orcid.org/0009-0008-6757-7660</p></bio><email xlink:type="simple">mariabulanova98@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1397-6208</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Панина</surname><given-names>О. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Panina</surname><given-names>O. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Панина Ольга Борисовна – доктор мед. наук, профессор, заведующая кафедрой акушерства и гинекологии факультета фундаментальной медицины ФГБОУ ВО “Московский государственный университет имени М.В. Ломоносова”; заведующая отделом гинекологии и репродуктивной медицины Медицинского научно-образовательного центра ФГБОУ ВО “Московский государственный университет имени М.В. Ломоносова”, Москваhttp://doi.org/0000-0003-1397-6208</p></bio><bio xml:lang="en"><p>Olga B. Panina – MD, Doct. of Sci. (Med.), Professor, Head of the Department of Obstetrics and Gynecology of Faculty of Medicine, Lomonosov Moscow State University; Head of the Department of Gynecology and Reproductive Medicine, Medical Research and Educational Center, Lomonosov Moscow State University, Moscowhttp://doi.org/0000-0003-1397-6208</p></bio><email xlink:type="simple">mariabulanova98@gmail.com</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">ФГБОУ ВО “Московский государственный университет имени М.В. Ломоносова”; &#13;
ГБУЗ “Городская клиническая больница №67 имени Л.А. Ворохобова ДЗ города Москвы”<country>Россия</country></aff><aff xml:lang="en">Lomonosov Moscow State University; L.A. Vorohobov City Clinical Hospital No. 67<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">ГБУЗ “Городская клиническая больница №67 имени Л.А. Ворохобова ДЗ города Москвы”<country>Россия</country></aff><aff xml:lang="en">L.A. Vorohobov City Clinical Hospital No. 67<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru">ФГБОУ ВО “Московский государственный университет имени М.В. Ломоносова”<country>Россия</country></aff><aff xml:lang="en">Lomonosov Moscow State University<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>28</day><month>11</month><year>2025</year></pub-date><volume>31</volume><issue>4</issue><fpage>43</fpage><lpage>53</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Буланова М.М., Шамугия В.В., Панина О.Б., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Буланова М.М., Шамугия В.В., Панина О.Б.</copyright-holder><copyright-holder xml:lang="en">Bulanova M.M., Shamugiya V.V., Panina O.B.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://usfd.vidar.ru/jour/article/view/339">https://usfd.vidar.ru/jour/article/view/339</self-uri><abstract><sec><title>Актуальность</title><p>Актуальность. Преэклампсия является тяжелым акушерским осложнением, приводящим к неблагоприятным исходам беременности и родов. Существующие многофакторные модели позволяют сформировать группы высокого риска развития преэклампсии, но задача по улучшению точности прогнозирования по-прежнему сохраняет актуальность. Поэтому продолжается поиск дополнительных предикторов развития преэклампсии.</p></sec><sec><title>Цель исследования</title><p>Цель исследования: выявление особенностей допплерографических показателей кровотока в междолевых почечных и глазных артериях у беременных в динамике (в 11–14 и в 19–21 нед гестации) при низком и высоком риске развития преэклампсии, рассчитанном в программном обеспечении Аstraia.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Выполнялось ультразвуковое исследование глазных и почечных артерий у пациенток при проведении пренатального скрининга в 11–14 и 19–21 нед беременности. Далее сравнивали показатели скорости, индекс резистентности, пульсационный индекс и отношение систолических пиков кровотока в глазных артериях, а также индекс резистентности в почечных артериях в динамике у пациенток с высоким и низким индивидуальным комбинированным риском развития преэклампсии.</p></sec><sec><title>Результаты</title><p>Результаты. У пациенток группы высокого риска отмечено снижение резистентности кровотока в глазной артерии. В группе низкого риска наблюдалось увеличение индекса резистентности в почечных артериях, максимальной систолической скорости кровотока в глазной артерии, увеличение отношения DV/P2 и снижение PR.</p></sec><sec><title>Заключение</title><p>Заключение. В группе низкого риска развития преэклампсии показатели кровотока изменялись с течением беременности, вероятно, в связи с адаптационными механизмами сердечно-сосудистой системы. В группе высокого риска развития преэклампсии практически отсутствовали физиологические изменения кровотока с течением беременности.</p></sec></abstract><trans-abstract xml:lang="en"><p>Preeclampsia is a severe obstetric complication that leads to adverse pregnancy and delivery outcomes. Existing multifactorial models make it possible to identify high-risk groups for the development of preeclampsia, but the task of improving prediction accuracy remains relevant. Therefore, the search for additional predictors of preeclampsia continues.</p><sec><title>Objective</title><p>Objective. To identify specific features of Doppler indices of blood flow in the interlobar renal arteries and ophthalmic arteries in pregnant women over time (at 11–14 and 19–21 weeks of gestation) in groups with low and high risk of developing preeclampsia, as calculated using the Astraia software.</p></sec><sec><title>Materials and Methods</title><p>Materials and Methods. Ultrasound examinations of the maternal ophthalmic and renal arteries were performed during prenatal screening at 11–14 and 19–21 weeks of pregnancy. Next, we compared flow velocity parameters, resistance index, pulsatility index, and the ratio of peak systolic velocities in the ophthalmic arteries, as well as the resistance index in the renal arteries, over time in patients with low and high individual combined risk of preeclampsia.</p></sec><sec><title>Results</title><p>Results. In the high-risk group, a decrease in blood flow resistance in the ophthalmic artery was observed. In the low-risk group, there was an increase in the resistance index in the renal arteries, an increase in peak systolic velocity in the ophthalmic artery, an increase in the DV/P2 ratio, and a decrease in PR.</p></sec><sec><title>Conclusions</title><p>Conclusions. In the low-risk group, blood flow parameters changed as pregnancy progressed, probably due to cardiovascular adaptive mechanisms. In the high-risk group, physiological changes in blood flow during pregnancy were nearly absent.  </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>преэклампсия</kwd><kwd>акушерство</kwd><kwd>ранний пренатальный скрининг</kwd><kwd>допплерография сосудов глаза</kwd><kwd>допплерография почек</kwd><kwd>ультразвуковая диагностика</kwd></kwd-group><kwd-group xml:lang="en"><kwd>preeclampsia</kwd><kwd>obstetrics</kwd><kwd>first trimester screening</kwd><kwd>ophthalmic artery Doppler ultrasound</kwd><kwd>renal artery Doppler ultrasound</kwd><kwd>ultrasound</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">James P.R., Nelson-Piercy C. Management of Hypertension before, during, and after Pregnancy. Heart. 2004; 90 (12): 1499–1504. https://doi.org/10.1136/hrt.2004.035444</mixed-citation><mixed-citation xml:lang="en">James P.R., Nelson-Piercy C. 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