usfdУльтразвуковая и функциональная диагностикаUltrasound & Functional Diagnostics1607-07712408-9494Vidar Ltd.10.24835/1607-0771-2022-4-30-42usfd-42Research ArticleУльтразвуковая диагностика в акушерстве и гинекологииObstetrics and Gynecology UltrasoundПиковая систолическая скорость кровотока в средней мозговой артерии и кардио-торакальный индекс у плодов с анемией тяжелой степени и водянкой плодаMiddle cerebral artery peak systolic velocity and cardiothoracic ratio in fetuses with severe anemia and hydropshttps://orcid.org/0000-0001-8469-5775МакогонА. В.MakogonA. V.

Макогон Аркадий Вилленович - к.м.н., руководитель группы медицины плода

Новосибирск

A.V. Makogon – M.D., Ph.D., Head of Fetal Medicine Group, Avicenna Medical Center

Novosibirsk

makogon@ngs.ruМЦ “Авиценна” ГК “Мать и Дитя”РоссияAvicenna Medical Center, Mother & Child Group of CompaniesRussian Federation202221012024043042Copyright © Макогон А.В., 20242024Макогон А.В.Makogon A.V.This work is licensed under a Creative Commons Attribution 4.0 License.https://usfd.vidar.ru/jour/article/view/42Цель

Цель: изучить показатели пиковой систолической скорости кровотока в средней мозговой артерии и кардио-торакального индекса у плодов, страдающих анемией тяжелой степени, осложненной водянкой плода, и сравнить их с показателями плодов, имеющих анемию тяжелой степени без признаков водянки.

Материал и методы

Материал и методы: сформированы 3 группы беременных без врожденных аномалий развития у плодов. В группу 1 (n = 13) включены беременные c анемией плода тяжелой степени в сочетании с водянкой и с известным катамнезом (все беременности одноплодные). В группу 2 (n = 11) включены беременные с анемией плода тяжелой степени без признаков водянки и с известным катамнезом (все беременности одноплодные). В группах 1 и 2 выполнялись многократные внутриутробные трансфузии. Группа 3 (n = 368) представлена случаями нормально завершившейся беременности для определения нормативных значений кардио-торакального индекса плода.

Результаты

Результаты: в группах 1 и 2 достоверные различия в значениях пиковой систолической скорости кровотока в средней мозговой артерии не выявлены (Р = 0,093). Значения кардио-торакального индекса в группах 1 и 2 достоверно различаются (Р = 0,035). При более тяжелой анемии, сопро вождающейся водянкой плода, кардиомегалия выражена в большей степени, чем в случаях анемии тяжелой степени без водянки плода.

Выводы

Выводы: более тяжелая анемия сопровождается более выраженной кардиомегалией, что позволяет рассчитывать на кардио-торакальный индекс как на маркер тяжести состояния плода при анемии.

Objective

Objective: to assess and compare the values of peak systolic velocity in the middle cerebral artery (PSV MCA) and cardiothoracic ratio (CTR) in groups of fetuses suffering from severe anemia with hydrops fetalis and severe anemia without hydrops.

Material and methods

Material and methods: pregnant women with no fetal congenital abnormalities were divided to the 3 groups. The group 1 (n = 13) consisted of women with singleton pregnancy with severe fetal anemia with hydrops. The group 2 (n = 12) consisted of women with singleton pregnancy with severe fetal anemia without signs of hydrops. Multiple intrauterine transfusions were performed in groups 1 and 2. Women with normal pregnancy and outcomes were included to the group 3 (n = 368) for assessing of normal CTR values in fetuses.

Results

Results: there were no significant differences of PSV MCA values between groups 1 and 2 (P = 0.093). On the other hand, the significant differences of CTR values obtained between groups 1 and 2 (P = 0.035). The CTR values in group 1 were higher than in group 2.

Conclusion

Conclusion: CTR value can be considered as an indicator of condition severity in fetuses with severe anemia.

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The authors declare that there are no conflicts of interest present.