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Ultrasound in Diagnosis of Inflammatory Bowel Diseases in Children

Abstract

There were examined 24 patients with verified Crohn’s disease and 37patients with verified ulcerative colitis. 30 patients without any clinical and laboratory data of the gastrointestinal diseases were included in to control group. Bowel ultrasound was done without any preparation and contrast enhancement. Sensitivity of the test “bowel wall thickness >2.5 mm - inflammatory bowel disease” - 90.2%, specificity - 100.0%, positive predictive value - 100.0%, negative predictive value - 83.3%, and AUC - 0.957. Sensitivity of the test “doppler signals amount in bowel wall >2 - inflammatory bowel disease” - 93.4%, specificity - 100.0%, positive predictive value - 100.0%, negative predictive value - 88.2%, and AUC - 0.967. Sensitivity of the test “stage 2 according Limberg score - active Crohn’s disease” - 100.0%, specificity - 66.7%, positive predictive value - 90.0%, negative predictive value - 100.0%, and AUC - 0.935. Significant differences in pathological vascularization, ascites, terminal ileum affection, mesentery and (or) omentum inflammatory infiltration, and lymph nodes size were revealed between group of Crohn’s disease and ulcerative colitis (P < 0.05 for all comparisons). Significant differences in pathological vascularization during the activity and remission periods were revealed in all groups; in lymphatic nodes size - in group of ulcerative colitis and combined group of bowel inflammatory disease; in ascites, terminal ileum affection, and mesentery and (or) omentum inflammatory infiltration - in group of Crohn’s disease (P < 0.05 for all comparisons).

About the Authors

M. I. Pykov
Russian Medical Academy of Postgraduate Education
Russian Federation


Ya. A. Galkina
Russian Medical Academy of Postgraduate Education
Russian Federation


A. M. Demina
Morozov Children’s City Clinical Hospital
Russian Federation


M. D. Mitkova
Russian Medical Academy of Postgraduate Education
Russian Federation


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For citations:


Pykov M.I., Galkina Ya.A., Demina A.M., Mitkova M.D. Ultrasound in Diagnosis of Inflammatory Bowel Diseases in Children. Ultrasound & Functional Diagnostics. 2016;(1):45-56. (In Russ.)

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