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Assessment of Efficacy and Safety of HIFU-ablation in Uterine Myoma Treatment Considering Nodes Localization

Abstract

Study results of the uterine myoma HIFU-ablation considering nodes localization (anterior or posterior wall) in 109 patients were presented. 179 nodes underwent treatment. 122 (68%) myomas were located at the anterior wall, 57 (32%) - at the posterior wall. Treatment efficacy was assessed by MRI (in 2-4 weeks) and ultrasound (6-7, 12-14, and 24-26 months). There was not any significant difference in application frequency of lens with different focal distance (150 and 180 mm) and treatment duration for myomas located at anterior and posterior walls. There was not any significant difference in volume of ablation between myomas at anterior and posterior walls according to MRI (in 2-4 weeks after HIFU-ablation). There was not any significant difference in volume of reduction between myomas at anterior and posterior walls according to ultrasound (6-7, 12-14, and 24-26 months after HIFU-ablation). The lowest volume of ablation was noticed in myomas with hyperintense characteristics on MRI irrespective of myoma localization (P < 0.05 for both comparisons). Treatment was more successful in myomas with hypointense characteristics on MRI (P < 0.05 for both comparisons). There was not any significant difference in recurrence frequency between myomas at anterior and posterior walls.

About the Authors

G. I. Nazarenko
Bank of Russia General Medical Center
Russian Federation


T. V. Krasnova
Bank of Russia General Medical Center
Russian Federation


I. V. Tonkonogova
Bank of Russia General Medical Center
Russian Federation


E. G. Bogdanova
Bank of Russia General Medical Center
Russian Federation


M. A. Prilutskaya
Bank of Russia General Medical Center
Russian Federation


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Review

For citations:


Nazarenko G.I., Krasnova T.V., Tonkonogova I.V., Bogdanova E.G., Prilutskaya M.A. Assessment of Efficacy and Safety of HIFU-ablation in Uterine Myoma Treatment Considering Nodes Localization. Ultrasound & Functional Diagnostics. 2016;(1):29-39. (In Russ.)

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ISSN 1607-0771 (Print)
ISSN 2408-9494 (Online)