Ultrasound diagnosis of calcium pyrophosphate deposition disease
https://doi.org/10.24835/1607-0771-337
Abstract
Calcium pyrophosphate deposition disease (CPPD) is one of the most common inflammatory arthropathies. It is characterized by the deposition of calcium pyrophosphate dihydrate (CPPD) crystals within joints and periarticular tissues. In routine clinical practice, imaging plays a central role in the diagnosis of CPPD. In recent years, ultrasound has emerged as a leading modality for early detection of crystal deposits across various anatomical regions, for monitoring disease progression, and for guiding aspiration procedures. The article presents a pictorial literature review highlighting the role of ultrasound in the diagnosis of calcium pyrophosphate deposition disease. Based on current clinical recommendations, the main ultrasound features of CPPD are described (detection of calcium pyrophosphate deposits in fibrous and hyaline cartilage, tendons, joint capsule, and intra-articular contents) allowing for correct interpretation of findings for timely diagnosis, differential diagnosis, and dynamical assessment during therapy.
About the Author
E. V. Polukhina
Postgraduate Institute for Public Health Workers; 9, Krasnodarskaya str., Khabarovsk 680009, Russian Federation
Russian Federation
Russian Federation
Elena V. Polukhina – MD, Doct. of Sci. (Med.), Associate Professor, Professor of Division of Rаdiology and Functional Diagnostics, Postgraduate Institute for Public Health Workers, Khabarovsk
https://orcid.org/0000-0002-8760-4880
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Review
For citations:
Polukhina E.V. Ultrasound diagnosis of calcium pyrophosphate deposition disease. Ultrasound & Functional Diagnostics. 2025;31(4):93-104. (In Russ.) https://doi.org/10.24835/1607-0771-337
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