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Comparison of two-dimensional shear wave elastography and transient elastography in liver fibrosis staging

https://doi.org/10.24835/1607-0771-2022-4-10-22

Abstract

Objective: to compare liver stiffness cut-off values for assessing liver fibrosis using two-dimensional shear wave elastography with literature data on results obtained using equipment from the same vendor.

Material and methods: the study included 54 women and 48 men aged from 22 to 86 years (median – 56 years), who were underwent transient elastography (FibroScan, Echosens, France) and two-dimensional shear wave elastography (Aplio 500, Canon Medical Systems, Japan) during routine follow-up for various chronic liver diseases. A comparative analysis of the two-dimensional shear wave elastography results according to two stratification systems (METAVIR score system and Baveno VI consensus criteria) was carried out with a study used same vendor equipment. Transient elastography was used as the reference method in both studies.

Results: there was a strong direct correlation between liver stiffness measured by transient elastography and two-dimensional shear wave elastography (r = 0.790, P < 0.001). The cut-off values for liver fibrosis staging according to METAVIR score system and to Baveno VI consensus criteria in the studies used the single vendor equipment were comparable. Thus, the cut-off value for F4 stage of liver fibrosis was 10.3 kPa (own data) versus 10.5 kPa, the cut-off value for high probability of presence of compensated advanced chronic liver disease – 11.3 kPa (own data) versus 10.6 kPa.

Conclusions: two-dimensional shear wave elastography is highly informative for liver fibrosis assessment according to both systems (METAVIR score system and Baveno VI consensus criteria). The cut-off values obtained with the use of single vendor equipment are comparable.

Keywords


About the Authors

O. M. Protsyk
Medical Center Vivea
Russian Federation

O.M. Protsyk – M.D., PhD., Head of Ultrasound Diagnostics Department

Khabarovsk



S. L. Shvyrev
Federal Research Institute for Health Organization and Informatics
Russian Federation

S.L. Shvyrev – M.D., Ph.D., Deputy Director, Department of Regulatory Information Service Center

Moscow



M. D. Mitkova
Russian Medical Academy of Continuous Professional Education
Russian Federation

M.D. Mitkova – M.D., Ph.D., Associate Professor, Diagnostic Ultrasound Division

Moscow



V. V. Kapustin
Yevdokimov Moscow State University of Medicine and Dentistry
Russian Federation

V.V. Kapustin – M.D., Ph.D., Professor, Division of Radiology

Moscow



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For citations:


Protsyk O.M., Shvyrev S.L., Mitkova M.D., Kapustin V.V. Comparison of two-dimensional shear wave elastography and transient elastography in liver fibrosis staging. Ultrasound & Functional Diagnostics. 2022;(4):10-22. (In Russ.) https://doi.org/10.24835/1607-0771-2022-4-10-22

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ISSN 1607-0771 (Print)
ISSN 2408-9494 (Online)