Shear wave elastography in recognition of metastatic axillary lymph nodes in women with breast cancer

Ultrasound examination of axillary lymph nodes in 71 women aged 25 to 76 years with histologically confirmed breast cancer was performed. All patients had suspicion for metastases to the axillary lymph nodes. All women were examined using ultrasound system Aplio 500 (Toshiba, Japan) with linear transducer 7-18 MHz. The first group of patients consisted of 33 women with confirmed metastatic lymph nodes, the second group - 38 patients with hyperplasia of lymphoid reticular tissue. Significant difference (P < 0.001) in Young’s modulus values between metastatic (median - 94.0 kPa, 2.5-97.5^th percentiles - 14.0-150.0 kPa) and benign (median - 18.3 kPa, 2.5-97.5^th percentiles - 6.2-66.4 kPa) axillary lymph nodes was revealed. Stiffness assessment was highly effective for metastatic axillary lymph nodes diagnosis (AUC - 0.920). The best diagnostic efficiency in breast cancer metastatic axillary lymph nodes detection was achieved at the cut-off value of Young’s modulus equal to 26.1 kPa (shear wave speed - 2.95 m/s) (sensitivity - 85%, specificity - 82%).

ультразвуковая эластография, эластография сдвиговой волной, рак молочной железы, лимфатические узлы, модуль Юнга, скорость сдвиговой волны, ultrasound elastography, shear wave elastography, breast cancer, lymph nodes, Young modulus, shear wave velocity

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