Gray-scale median analysis in assessment of carotid arteries atherosclerotic plaques and its clinical value

Carotid arteries atherosclerotic plaques were assessed using grey-scale median (GSM) analysis (iU22 (Philips, Netherlands) scanner and workstation MultiVox (Gammamed, Russia)). GSM analysis results of 25 atherosclerotic plaques obtained by MultiVox (GSM MV) and Adobe Photoshop (GSM AP) were compared at the first stage of the study. There were good correlation and agreement (Bland-Altman method) between GSM MV and GSM AP results. Good intraobserver and interobserver agreement was demonstrated for GSM MV measurements. At the second stage of the study, 51 carotid arteries atherosclerotic plaques with more than 70% stenosis were investigated (44 patients aged 51-83 years who underwent carotid endarterectomy with subsequent atherosclerotic plaques histological study). There was not any significant difference in GSM MV between subgroups with stable and unstable atherosclerotic plaques: 52.5 (42.0-64.6) against 46.4 (34.4-59.7) (median, interquartile range). Significant dispersion of GSM MV values in subgroup of unstable atherosclerotic plaques was determined. It makes more reasonable to do GSM MV evaluation in different zones of atherosclerotic plaques. GSM MV can be used in medical practice instead of GSM AP.

ультразвуковая диагностика, сонная артерия, атеросклеротическая бляшка, медиана серой шкалы (GSM), воспроизводимость, согласованность, каротидная эндартерэктомия, гистологическое исследование, duplex ultrasound, carotid artery, atherosclerotic plaque, grey-scale median (GSM), reproducibility, agreement, carotid endarterectomy, histology

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