Prenatal prediction of outcomes in congenital diaphragmatic hernia based on fetal 3D/4D ultrasound lung morphometry and histogram analysis (a pilot study)
https://doi.org/10.24835/1607-0771-2022-1-19-26
Abstract
Objective: to develop 4D ultrasound criteria of lung assessment in fetuses with congenital diaphragmatic hernia, with potential use for outcomes prediction. Material and methods: the results of 4D ultrasound in fetuses with gestational age 26-38 weeks with congenital diaphragmatic hernia (14 cases) were analyzed. According to the pregnancy outcomes, the fetuses were divided into two subgroups: survived (n = 10) and deceased in the early neonatal period (n = 4). Ultrasound examinations performed with the use of Virtual Organ Computer-aided AnaLysis (VOCAL) and 4D Histogram software of Voluson 730 Expert (GE Healthcare, USA) with 4D convex transabdominal transducer (4-8.5 MHz). The fetal lung-to-head ratio (contralateral lung volume to head circumference ratio) (1) and lung-to-lung echogenicity ratio with histogram analyses (2) were evaluated. Results: the significant differences of fetal lung-to-head ratio and also in lung-to-lung echogenicity ratio with histogram analyses between the two groups were obtained (P = 0.0047). Conclusion: fetal lung-to-head ratio (1) and lung-to-lung echogenicity ratio with histogram analyses (2) are possible to use for early neonatal death prediction.
About the Author
A. N. Chukanov
Belarusian Medical Academy of Postgraduate Education
Russian Federation
Russian Federation
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For citations:
Chukanov A.N. Prenatal prediction of outcomes in congenital diaphragmatic hernia based on fetal 3D/4D ultrasound lung morphometry and histogram analysis (a pilot study). Ultrasound & Functional Diagnostics. 2022;(1):19-26. (In Russ.) https://doi.org/10.24835/1607-0771-2022-1-19-26
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