Ultrasound in Uterine Endometrial Stromal Sarcoma Diagnosis
Abstract
12 patients aged from 33 up to 67 years old with uterine endometrial stromal sarcoma were included into the study. Low-grade endometrial stromal sarcoma was diagnosed in 9 from 12 (75.0%) patients. Metastases of different localization were revealed in 6 from 9 (66.7%) patients. High-grade endometrial stromal sarcoma was diagnosed in 3 from 12 (25.0%) patients; recurrence of the disease was revealed in 2 from 3 (66.7%) patients owing the non-radical treatment. Typical ultrasound signs of endometrial stromal sarcoma were hypoechoic lesion in uterine cavity, unclear boundary with myometrium.
About the Authors
M. A. Chekalova
N.N. Blokhin Russian Cancer Research Center
Russian Federation
Russian Federation
I. K. Mnatsakanyan
N.N. Blokhin Russian Cancer Research Center
Russian Federation
Russian Federation
L. K. Mnatsakanyan
Limited Company Rosgosstrakh Medicine
Russian Federation
Russian Federation
References
1. Лекции по онкогинекологии: Учебник для студентов / Под общ. ред. акад. РАН и РАМН М.И. Давыдова, проф. В.В. Кузнецова; под ред. В.М. Нечушкиной. М.: МЕДпресс-информ, 2009. 432 с.
2. Kahanpaa K.V., Wahlstrom T., Grohn P. et al. Sarcomas of the uterus: a clinicopathologic study of 119 patients // Obstet. Gynecol. 1989. V. 67. No. 3. P. 417-424.
3. Ashraf-Ganjoei T., Behtash N., Shariat M., Mosavi A. Low grade endometrial stromal sarcoma of uterine corpus, a clinico-pathological and survey study in 14 cases // World J. Surg. Oncol. 2006. V. 4. P. 50.
4. WHO Classification of Tumours of Female Reproductive Organs / Ed. by R.J. Kurman, M.L. Carcangiu, C.S. Herrington, R.H. Young. Lyon: IARC Press, 2014. 307 p.
5. Ali R.H., Rouzbahman M. Endometrial stromal tumours revisited: an update based on the 2014 WHO classification // J. Clin. Pathol. 2015. V. 68. No. 5. P. 325-332.
6. Мнацаканян Л.К. Клинико-ультразвуковая диагностика злокачественных неэпителиальных опухолей тела матки: Автореф. дис. … канд. мед. наук. М., 2009. 26 с.
7. Лазарева Н.И. Злокачественные мезенхимальные опухоли женских половых органов (клиника, диагностика, лечение, факторы прогноза): Автореф. дис. … докт. мед. наук. М., 2003. 47 с.
8. Cohen I. Endometrial pathologies associated with postmenopausal tamoxifen treatment // Gynecol. Oncol. 2004. V. 2. P. 256-266.
9. WHO Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs / Ed. by F.A. Tavassoli, P. Devilee. Lyon: IARC Press, 2003. P. 233-236.
10. Puliyath G., Nair M.K. Endometrial stromal sarcoma: a review of the literature // Indian J. Med. Paediatr. Oncol. 2012. V. 33. No. 1. P. 1-6.
11. Chan J.K., Kawar N.M., Shin J.Y. et al. Endometrial stromal sarcoma: a population-based analysis // Br. J. Cancer. 2008. V. 99. No. 8. P. 1210-1215.
12. Somma A., Falleti J., Di Simone D. et al. Cystic variant of endometrial stromal sarcoma: report of two cases // Int. J. Surg. Pathol. 2012. V. 21. No. 3. P. 278-281.
13. Perez-Montiel D., Salmeron A.A., Dominguez Malagon H. Multicystic endometrial stromal sarcoma // Ann. Diagn. Pathol. 2004. V. 8. No. 4. P. 213-218.
14. Larson B., Silfversward C., Nilsson B., Peltersson F. Endometrial stromal sarcoma of the uterus. A clinical and histopathological study. The Radiumhemmet series 1936-1981 // Eur. J. Obstet. Gynecol. Reprod. Biol. 1990. V. 35. No. 2-3. P. 239-249.
15. Holland C. The rare endometrial stromal sarcoma arises from stromal elements of the endometrium. Endometrial cancer // Obstet. Gynaecol. Reprod. Med. 2010. V. 20. P. 12.
16. Evans H.L. Endometrial stromal sarcoma and poorly differentiated endometrial sarcoma // Cancer. 1982. V. 50. No. 10. P. 2170-2182.
17. Oliva E., Young R.H., Clement P.B., Scully R.E. Myxoid and fibrous endometrial stromal tumors of the uterus: a report of 10 cases // Int. J. Gynecol. Pathol. 1999. V. 18. No. 4. P. 310-319.
18. Чекалова М.А. Ультразвуковая диагностика злокачественных новообразований матки: Автореф. дис. … докт. мед. наук. М., 1998. 46 с.
19. Зыкин Б.И., Медведев М.В. Допплерография в гинекологии. М.: Реальное время, 2000. 152 с.
20. Kim J.A., Lee M.S., Choi J.S. Sonographic findings of uterine endometrial stromal sarcoma // Korean J. Radiol. 2006. V. 7. No. 4. P. 281-286.
21. Cacciatore B., Lehtovirta P., Wahlstrom T., Ylostalo P. Ultrasound findings in uterine mixed mullerian sarcomas and endometrial stromal sarcomas // Gynecol. Oncol. 1989. V. 35. No. 3. P. 290-293.
22. Sohaib S.A., Verma H., Attygalle A.D., Ind T.E. Imaging of uterine malignancies // Semin. Ultrasound CT MR. 2010. V. 31. No. 5. P. 377-387.
Review
For citations:
Chekalova M.A., Mnatsakanyan I.K., Mnatsakanyan L.K. Ultrasound in Uterine Endometrial Stromal Sarcoma Diagnosis. Ultrasound & Functional Diagnostics. 2016;(6):40-51. (In Russ.)
Views:
103
Email this article 