Dynamics of 2D Speckle Tracking Echocardiography Parameters after Primary Anterior ST-segment Elevation Myocardial Infarction (STEMI)

Aim of the study was to assess the cardiac biomechanic changes after the primary anterior ST-segment elevation myocardial infarction according to the 2D speckle tracking echocardiography. 35patients with acute Q-wave myocardial infarction were admitted within the 24 hours from the disease onset. Echocardiography including 2D speckle tracking was performed on 3^rd (T1), 7^th (T2), and 14^th (T3) day and in 6 months (T4) after the myocardial infarction using Vivid E9 (GE Healthcare, USA) ultrasound system. Patients were divided into two groups: with left ventricular remodeling (14 people) and without it (20 people). Emergency reperfusion therapy was performed in all patients, in 25 (71%) cases within the first 6 hours. Strain decrease identified cardiac function recovery in early postinfarction period. The improvement of global longitudinal strain occurred already to the point T2, while the changes in rotation data in these terms were not observed. Despite the fact that apical rotation and peak S apical rotation rate were in normal range, peak S apical rotation rate increased significantly to the 14^th day (T3). Peak S apical rotation rate and peak S basal rotation rate decreased significantly by the 6 months (T4) of follow-up period. By that time end-systolic volume, end-diastolic volume, and stroke index significantly increased. In patients with left ventricular remodeling at 6-month follow-up period decrease of left ventricle ejection fraction and global longitudinal strain were noticed, indicating the deterioration of systolic function.

эхокардиография в режиме 2D speckle tracking, глобальная продольная деформация, базальная ротация, систолическая скорость базальной ротации, апикальная ротация, систолическая скорость апикальной ротации, инфаркт миокарда с подъемом сегмента ST, Q-инфаркт миокарда, ремоделирование левого желудочка, 2D speckle tracking echocardiography, longitudinal strain, basal rotation, peak S basal rotation rate, apical rotation, peak S apical rotation rate, ST-segment elevation myocardial infarction (STEMI), Q-wave myocardial infarction, left ventricular remodeling

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