A rare case of comprehensive diagnosis of diffuse large B-cell lymphoma of the ovary detected in the early postpartum period by ultrasound
https://doi.org/10.24835/1607-0771-316
Abstract
Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous orphan lymphoproliferative disorder characterized by an aggressive course. Due to its unusual nature, primary ovarian lymphoma lacks specific clinical features and may be mistaken for other types of ovarian malignancies. It poses a dual diagnostic and therapeutic challenge. Imaging plays a central role in diagnosing ovarian lymphoma, and radiologists should be familiar with the sonographic, computed tomography (CT), and magnetic resonance imaging (MRI) features of this condition in order to guide diagnostic workup and avoid unnecessary adnexectomy. Particular attention should be paid to thorough evaluation of the adnexa during preconception screening and during routine obstetric ultrasound, which are typically performed at least three times throughout pregnancy: in early gestation and at 11–14 weeks and 19–21 weeks of pregnancy.
About the Authors
A. I. IshchenkoRussian Federation
Anatoliy I. Ishchenko – MD, Doct. of Sci. (Med.), Professor of the Department of Obstetrics and Gynecology No. 1, N.V. Sklifosovsky Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow
https://orcid.org/0000-0003-3338-1113
N. I. Borisova
Russian Federation
Natalya I. Borisova – MD, PhD, Deputy Chief Physician for Obstetrics and Gynecology at the Sechenov Center for Maternity and Childhood, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow
https://orcid.org/0009-0007-7350-7960
T. T. Demura
Russian Federation
Tatyana A. Demura – MD, Doct. of Sci. (Med.), Professor, Vice-rector for scientific activity; Director of Institute for clinical morphology and digital pathology, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow
https://orcid.org/0000-0002-6946-6146
N. B. Paramonova
Russian Federation
Nina B. Paramonova – MD, PhD, Deputy Director of the Institute of Clinical Morphology and Digital Pathology, Head of the Centralized Pathological Anatomical Department, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow
https://orcid.org/0000-0001-5380-7113
A. M. Kovrigina
Russian Federation
Alla M. Kovrigina – Doct. of Sci. (Biol.), Head of the Pathology Department, National Medical Research Center for Hematology; Professor of the Institute of Clinical Morphology and Digital Pathology, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow
https://orcid.org/0000-0002-1082-8659
K. M. Shchepina
Russian Federation
Karina M. Shchepina – pathologist, Pathology department, National Medical Research Center for Hematology, Moscow
https://orcid.org/0009-0006-6079-8239
N. M. Khovanskaya
Russian Federation
Nina M. Khovanskaya – radiologist, Department of Radiology, University Clinical Hospital No. 2, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow
https://orcid.org/0009-0006-9120-7358
E. V. Minashkina
Russian Federation
Elena V. Minashkina – ultrasound diagnostics doctor, clinical diagnostic department, Sechenov Center for Maternity and Childhood, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow
https://orcid.org/0009-0004-3548-7944
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Review
For citations:
Ishchenko A.I., Borisova N.I., Demura T.T., Paramonova N.B., Kovrigina A.M., Shchepina K.M., Khovanskaya N.M., Minashkina E.V. A rare case of comprehensive diagnosis of diffuse large B-cell lymphoma of the ovary detected in the early postpartum period by ultrasound. Ultrasound & Functional Diagnostics. 2025;31(3):76-85. (In Russ.) https://doi.org/10.24835/1607-0771-316