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Difficulties in diagnosing Loeffler’s endocarditis

https://doi.org/10.24835/1607-0771-2022-3-41-48

Abstract

Loeffler’s endocarditis is a rare disease characterized by a progressive course, poor prognosis, and high mortality. Early non-invasive diagnosis of this disease is difficult due to the lack of a specific clinic and pathognomonic signs according to instrumental examinations. The article presents the clinical case of 52-year-old patient with an atypical (neurological) onset of the disease. Echocardiography revealed thrombosis of the left ventricle with a normal ejection fraction without signs of global and segmental dysfunction (4 months after neurological manifestations), which are signs of the second stage of Loeffler’s endocarditis. Despite the fact that there was no eosinophilia upon admission to the hospital, a careful study of the outpatient chart revealed a repeated increase in eosinophils (27, 77, and 64% in three studies with a two-month interval) 9 months before the onset of clinical manifestations. Despite therapy, the disease progresses with the formation of the left ventricle restrictive diastolic dysfunction (the third stage of Loeffler’s endocarditis), the signs of which were revealed 7 months after the onset of clinical manifestations.

About the Authors

E. V. Trubina
Altai Regional Cardiological Clinic
Russian Federation

Elena V. Trubina - M.D., Ph.D., Head of Functional Diagnostics Department

Barnaul



M. S. Surgutskaya
Altai Regional Cardiological Clinic
Russian Federation

M.D., Functional Diagnostics Department

Barnaul



A. V. Ott
Altai Regional Cardiological Clinic
Russian Federation

M.D., Ph.D., Department of Cardiology

Barnaul



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For citations:


Trubina E.V., Surgutskaya M.S., Ott A.V. Difficulties in diagnosing Loeffler’s endocarditis. Ultrasound & Functional Diagnostics. 2022;(3):41-48. (In Russ.) https://doi.org/10.24835/1607-0771-2022-3-41-48

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ISSN 1607-0771 (Print)
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