Results of contrast enhanced ultrasound in 3 patients with liver metastases are presented. The first case presents data of contrast enhanced ultrasound in diagnosis of multiple metastases of neuroendocrine pancreatic tumor which were not visualized in B-mode. Second and third cases (rectal cancer with liver metastases) did not show any new lesions in compare with B-mode.

Case report of adenovirus infection in renal transplant patient is presented. 6 years old patient with focal segmental glomerulosclerosis and stage 5 chronic kidney diseases underwent renal transplantation from the 54 years old living related donor. Kidney function started immediately. Transplant dysfunction was diagnosed on 19^th day after the surgery during ultrasound investigation. Adenovirus infection was revealed during renal transplant biopsy.

7 patients with ovarian pregnancy were examined with help of ultrasound. The age of patients ranged from 22 to 41 years old. Literature review (1989-2015) related to the problem of ovarian pregnancy ultrasound diagnosis was also done. According to the literature review and results of the study brief summary of ovarian pregnancy clinical and diagnostic characteristics was presented. Early diagnosis of ovarian pregnancy often allows choosing the organ-preserving surgery. Ultrasound signs of pelvis region in ovarian pregnancy were as follows: the absence of ovum in the uterus, free fluid in the pelvis, the lack of ovary visualization on the side of ovarian pregnancy or presence of enlarged ovary with markedly heterogeneous structure on the side of ovarian pregnancy with absence of any additional mass on the side of changed ovary. Ultrasound image of the ovarian pregnancy was presented as a typical ovum with live or dead embryo (typical for primary ovarian pregnancy), broad echogenic ring with echonegative content (typical for primary ovarian pregnancy), ovary which had intimately (deforming ovary) adjacent mass of irregular shape and heterogeneous structure, forming a single conglomerate with the ovary (typical for secondary ovarian pregnancy), irregularly shape and non-uniform mass (bigger than normal ovary) surrounded by the free fluid (blood imbibition of the ovary with rupture and intraperitoneal hemorrhage).

Case report of congenital multiple secundum atrial septal defects in 30 years old patient is described. Multiple (double) atrial septal defects were diagnosed by transesophageal echocardiography. Transthoracic echocardiography failed to visualize defects because of inadequate acoustic window. The exact size of defects (more than 40 mm) and their localization (adjacent to aorta) were determined by three-dimensional transesophageal echocardiography. Surgical closure of atrial septal defects using autologous pericardium was done.

Results of primary cutaneous melanoma ultrasound diagnosis with regard to skin layers involvement are presented. Value of ultrasound in disease extension assessment is given. Ultrasound image of cutaneous melanoma depends on tumor thickness. Thin tumor is characterized as follows: epidermis localization, wide base, spindle shape, regular far contour, distinct differentiation from the adjacent area, homogenous echostructure, and low echogenicity. Increase of tumor’s thickness causes diversity of the ultrasound image. Ultrasound allows assessing subcutaneous adipose tissue and its infiltration by primary tumor (level V of invasion by Clark staging system), presence of satellite metastases. Ultrasound assessment of primary melanoma invasion and its thickness correlates very well with morphological examination.

Retrospective analysis of urachal anomalies at period from 2005 up 2015 in 18 children was presented. 15 (83.3%) patients had urachal sinus due to absence of obliteration of the distal (umbilical) urachal part, 3 (16.7%) - urachal cyst due to absence of obliteration of the middle urachal part with suppuration in 2 cases. Tubular structure along the midline below the umbilicus was visualized in 8 (53.3%o) of 15 cases of urachal sinus during the ultrasound examination; it was combined with umbilical focal lesion visualization in 4 patients. Only umbilical focal lesion was visualized in 6 (40.0%) of 15 cases of urachal sinus with inflammatory changes in 2 patients. There was a false negative result in 1 (6.7%) of 15 cases of urachal sinus. Urachal cysts (3) were round or oval and localized along the median line of the abdomen. The cystic wall was hyperechoic without layer differentiation. There were heterogeneous internal structures in case of inflammation. Urachal cysts in case of inflammation cause acute abdominal syndrome.