Exercise echocardiography in left ventricular diastolic function assessment in patients with idiopathic left bundle branch block

34 patients (29-81 years old) with idiopathic left bundle branch block were examined. Mean QRS duration was 153.1 ± 24.5 ms (M ± σ). The control group included 18patients aged from 38 to 80 years old. Echocardiography with left ventricle diastolic function and global longitudinal strain assessment at rest and after exercise stress test were performed to all patients. At rest in the group with idiopathic left bundle branch block, in compare with the control group, lower values of global longitudinal strain (-15.6 ± 3.7 and -18.4 ± 3.1%, P = 0.037) and left ventricle twist (9.08 ± 4.59 and 13.96 ± 4.61°, P = 0.016) were observed, whereas significant differences in diastolic function parameters were absent. After exercise stress test in the group with idiopathic left bundle branch block, compared with the control group, lower values of E_mitr/A_mitr (0.74 ± 0.20 and 0.98 ± 0.30, P = 0.033) and average e’ (9.4 ± 4.0 and 12.7 ± 3.5 cm/s, P = 0.013); longer isovolumteric relaxation time (89.3 ± 19.6 and 67.5 ± 14.2 ms, P = 0.004); lower values of left atrium systolic filling fraction (58.1 ± 5.3 and 64.5 ± 4.5%, P = 0.026); lower values of left ventricle twist (6.82 ± 6.26 and 18.61 ± 6.90, P = 0.000); higher values of pulmonary artery systolic pressure (41.6 ± 8.5 and 32.4 ± 3.8 mm Hg, P = 0.020) were observed. No significant differences were found between two groups in global longitudinal strain after exercise stress test.

эхокардиография, диастолическая функция левого желудочка, диастолическая дисфункция левого желудочка, полная блокада левой ножки пучка Гиса, глобальная продольная деформация, скручивание, echocardiography, left ventricular diastolic function, left ventricular diastolic dysfunction, complete left bundle branch block, global longitudinal strain, twist

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